Born with or Acquired Later- Unveiling the Truth About Celiac Disease Development
Are you born with celiac or can you develop it? This question has puzzled many individuals, especially those experiencing symptoms of celiac disease. Celiac disease is an autoimmune disorder where the ingestion of gluten, a protein found in wheat, barley, and rye, triggers an immune response that damages the small intestine. Understanding whether celiac disease is an inherited condition or can develop later in life is crucial for diagnosis and treatment.
Research suggests that celiac disease is primarily an inherited condition. The risk of developing celiac disease is higher for individuals with a family history of the disease. Genes play a significant role in determining one’s susceptibility to celiac disease. Approximately 1 in 133 people in the United States have celiac disease, but only a fraction of them are diagnosed. Genetic testing can help identify individuals who are at a higher risk of developing the disease.
However, not everyone with celiac disease has a family history. Some individuals may develop the disease later in life, even after years of eating gluten without any issues. This phenomenon is known as “celiac disease onset in adulthood.” Factors that may trigger the onset of celiac disease in adulthood include infections, surgery, stress, and other autoimmune conditions. In these cases, the immune system becomes hyper-sensitive to gluten, leading to the development of celiac disease.
It is important to note that while genetics play a significant role in the development of celiac disease, environmental factors can also contribute to the onset of the disease. For instance, certain viral infections have been associated with the development of celiac disease. Additionally, exposure to gluten early in life may protect against the disease, while later exposure can increase the risk of developing celiac disease.
Diagnosis of celiac disease involves a combination of blood tests, an endoscopy with a biopsy of the small intestine, and a gluten challenge. Blood tests look for specific antibodies that are present in individuals with celiac disease. If the blood tests are positive, an endoscopy and biopsy are performed to confirm the diagnosis. Treatment for celiac disease involves a lifelong gluten-free diet, which can alleviate symptoms and prevent long-term complications.
In conclusion, while celiac disease is primarily an inherited condition, it can also develop later in life due to various factors. Understanding the genetic and environmental risk factors can help individuals with a family history of celiac disease or those experiencing symptoms to seek timely diagnosis and treatment. For those without a family history, it is essential to be aware of the potential triggers and seek medical advice if symptoms of celiac disease arise.
